Age-specific dementia prevalence increased with age from 0.8% (65–74.9 years) to 9.93% (85–89.9 years). At the consensus diagnostic review board, 118/163 were diagnosed with probable all-cause dementia, a prevalence of 13.6%. The EHR review identified 163/865 (18.8%) individuals as having cognitive dysfunction. Self-reported dementia diagnoses were positive in only 17.8% of ascertained dementia diagnoses. We compared the agreement between our newly ascertained dementia diagnoses with the existing self-reported dementia diagnoses. For those with probable dementia, a subtype was also determined, where possible. A diagnosis of probable dementia, possible dementia, or no dementia was agreed upon by a consensus diagnostic review board, comprised of a multidisciplinary team of clinical dementia experts who reviewed case vignettes and clinician assessment letters. Clinician assessments were performed when there was concern about a participant's cognition. Death certificate data were obtained separately. The EHR data sources include hospital and clinic letters, general practitioner and hospital referrals, prescribed medications, imaging and laboratory results. MethodsĮlectronic Health Records (EHR) of all participants were reviewed, and relevant information was extracted to form case vignettes for everyone with any record of cognitive dysfunction. Our aims were twofold:Ī) to describe a framework for identifying dementia in a cohort study.ī) to report the age-specific incidence and prevalence of all-cause dementia and dementia subtypes in 865 individuals in the LBC1936. The Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied on self-report or proxies for dementia such as cognitive tests.
0 kommentar(er)
